Competitive Strategies in Life Sciences by Basanta Kumara Behera & Ram Prasad & Shyambhavee Behera

Author:Basanta Kumara Behera & Ram Prasad & Shyambhavee Behera
Language: eng
Format: epub
ISBN: 9789811575907
Publisher: Springer Singapore

The entaeration process is associated with four types of mechanical accessories that increase the efficacy of aeration process. The additional mechanical devises are (1) agitator, (2) stirrer, (3) baffle, and (4) sparger (Fig. 2.12).

Fig. 2.12Schematic view of a typical stirred tank bioreactor showing different controlling systems

Agitators

Agitation is a mechanical process for mixing nutrients and oxygen, which can be available in adequate quantity and favour the growth of host cells or microbes to obtain quality product in good quantity. Agitation process also helps in bringing homogeneity in suspended host cells or microbes throughout the culture broth.

The size and structural getup of impeller mainly depend on the nature of host cells and the height of the vessel. A bigger size of bioreactor needs more than one impeller. Ideally, the impeller should be one-third of the fermenter diameter fitted above the base of the bioreactor. Mainly, the following types of impellers are in use for bioreactor (Fig. 2.13).

Fig. 2.13Different types of impellers used in bioreactor

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